Legumain Antibody (YA2469)

Legumain Antibody (YA2469) is a biotin-conjugated non-conjugated IgG antibody, targeting Legumain, with a predicted molecular weight of 49 kDa (observed band size: 36,57 kDa). Legumain Antibody (YA2469) can be used for WB experiment in human, mouse, rat background.

The related gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. The enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of The related gene may be associated with the majority of solid tumor types. The related gene has a pseudorelated gene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform.

5641

Predicted band size: 49 kDa; Observed band size: 36,57 kDa

Affinity Purified

Non-conjugated

Unmodified

Immunology

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

Q99538

WB: 1/500-1/1000

WB

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human Legumain