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  4. HP1 alpha Antibody (YA983)

HP1 alpha Antibody (YA983)

Cat. No.: HY-P81280B
User Guide for Antibodies

HP1 alpha Antibody (YA983) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA983), targeting HP1 alpha, with a predicted molecular weight of 22 kDa (observed band size: 22 kDa). HP1 alpha Antibody (YA983) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock
10 μL $70 Ask For Quote & Lead Time
50 μL $185 Ask For Quote & Lead Time
100 μL $300 Ask For Quote & Lead Time

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

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Description

HP1 alpha Antibody (YA983) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA983), targeting HP1 alpha, with a predicted molecular weight of 22 kDa (observed band size: 22 kDa). HP1 alpha Antibody (YA983) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human, mouse, rat background.

Background

The related gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The related gene has a pseudorelated gene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene ID

23468

Synonyms
CBX5; HP1A; Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha
Molecular Weight

Predicted band size: 22 kDa; Observed band size: 22 kDa

Purity

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Epigenetics and Nuclear Signaling

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

SwissProt ID

P45973

Dilution Ratio

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/20

Application

WB, IHC-F, IHC-P, ICC/IF, IP

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthetic peptide of human HP1 alpha

Documentation

HP1 alpha Antibody (YA983) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
HP1 alpha Antibody (YA983)
Cat. No.:
HY-P81280B
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