HLA DPB1 Antibody (YA3273)

HLA DPB1 Antibody (YA3273) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3273), targeting HLA DPB1, with a predicted molecular weight of 29 kDa (observed band size: 29 kDa). HLA DPB1 Antibody (YA3273) can be used for WB, IHC-P, ICC/IF, IP experiment in human background.

HLA-DPB belongs to the HLA class II beta chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its related gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

3115

Predicted band size: 29 kDa; Observed band size: 29 kDa

Affinity Chromatography

Non-conjugated

Unmodified

Immunology

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

P04440

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/50

WB, IHC-P, ICC/IF, IP

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human MHC Class II