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  4. GNB3 Antibody (YA2945)

GNB3 Antibody (YA2945)

Cat. No.: HY-P83200
User Guide for Antibodies

GNB3 Antibody (YA2945) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2945), targeting GNB3, with a predicted molecular weight of 37 kDa (observed band size: 37 kDa). GNB3 Antibody (YA2945) can be used for WB, IHC-P experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock
10 μL $70 Ask For Quote & Lead Time
50 μL $185 Ask For Quote & Lead Time
100 μL $300 Ask For Quote & Lead Time

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

GNB3 Antibody (YA2945) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2945), targeting GNB3, with a predicted molecular weight of 37 kDa (observed band size: 37 kDa). GNB3 Antibody (YA2945) can be used for WB, IHC-P experiment in human, mouse, rat background.

Background

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. The related gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in The related gene is associated with essential hypertension and obesity. The polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of The related gene have been described, but their full-length nature is not known.

Gene ID

2784

Synonyms
CSNB1H
Molecular Weight

Predicted band size: 37 kDa; Observed band size: 37 kDa

Purity

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Signal Transduction

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

SwissProt ID

P16520

Dilution Ratio

WB: 1/500-1/1000;IHC: 1/50-1/100

Application

WB, IHC-P

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthetic peptide of human GNB3

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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GNB3 Antibody (YA2945)
Cat. No.:
HY-P83200
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