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  2. Primary Antibodies
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  4. EPOR Antibody

EPOR Antibody

Cat. No.: HY-P81152
User Guide for Antibodies

EPOR Antibody is an unconjugated, approximately 56 kDa, rabbit-derived, anti-EPOR polyclonal antibody. EPOR Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, rat, and predicted: mouse, dog, cow, horse background without labeling.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

EPOR Antibody is an unconjugated, approximately 56 kDa, rabbit-derived, anti-EPOR polyclonal antibody. EPOR Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, rat, and predicted: mouse, dog, cow, horse background without labeling.

Background

The related gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, The receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of The related gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.

Gene ID

2057

Synonyms
erythropoietin receptor; EPO R; EPO Receptor; Erythropoietin receptor precursor; EPOR_HUMAN; MGC138358.
Molecular Weight

Predicted band size: 56kDa

Purity

affinity purified

Subcellular Location

Cell membrane; Single-pass type I membrane protein. Isoform EPOR-S: Secreted. Note=Secreted and located to the cell surface.

Conjugation

Non-conjugated

Modification

Unmodified

Product Categories

Primary Antibody; Rabbit Polyclonal Antibody

Clonality

Polyclonal

Host

Rabbit

Reactivity

Human, Rat

Predicted Reactivity

Mouse, Dog, Cow, Horse

Note: The predicted reactivity is for reference only, not as a product performance guarantee.
SwissProt ID

P19235

Dilution Ratio

WB: 1:500-2000;ELISA: 1:5000-10000;IHC-P: 1:100-500;IHC-F: 1:100-500;IF: 1:100-500

Application

WB, ELISA, IHC-P, IHC-F, ICC/IF

Appearance

Liquid

Formulation

Supplied in 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

KLH conjugated synthetic peptide derived from human EPOR: 301-450/508

Documentation

EPOR Antibody Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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EPOR Antibody
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HY-P81152
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