2. Epigenetics PI3K/Akt/mTOR
  3. AMPK
  4. A17

A17 is a bile acid analog with anti-non-alcoholic steatohepatitis (NASH) and anti-inflammatory activities. A17 reduces fatty acid (FA) uptake and promotes FA oxidation though inhibiting fatty acid translocase (Cd36) expression and activating AMPKα. A17 can be used for NASH research.

For research use only. We do not sell to patients.

A17 Chemical Structure

A17 Chemical Structure

CAS No. : 2568186-47-8

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Description

A17 is a bile acid analog with anti-non-alcoholic steatohepatitis (NASH) and anti-inflammatory activities. A17 reduces fatty acid (FA) uptake and promotes FA oxidation though inhibiting fatty acid translocase (Cd36) expression and activating AMPKα. A17 can be used for NASH research[1].

Molecular Weight

533.74

Formula

C31H51NO6
CAS No.
SMILES

O=CO[C@@H]1[C@]2([H])[C@@](CC[C@]3([C@@]2([H])CC[C@]3([H])[C@H](C)CCC(N[C@H](CO)C(C)C)=O)C)([H])[C@@]4([C@](C[C@@H](CC4)OC=O)([H])C1)C
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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A17 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

A172568186-47-8A 17A-17AMPKAMP-activated protein kinaseNASHanti-inflammatoryCd36AMPKαInhibitorinhibitorinhibit

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