2. Signaling Pathways
  3. Others
  4. Others
  5. Others Degrader

Others Degrader

Others Degraders (2):

Cat. No. Product Name Effect Purity
  • HY-160438B
    PBX-7011 TFA
    		Degrader
    PBX-7011 TFA is a derivative of camptothecin (HY-16560), which inhibits expressions of the cancer related survival genes DDX5, Survivin, Mcl-1 and XIAP in cells FaDu, degrades DDX5 proteins and exhibits anticancer activity.
  • HY-163564
    JYQ-194
    		Degrader
    JYQ-194 is a proteolysis targeting chimera (PROTAC) designed to target human Parkinson's disease protein 7 (PARK7). It operates by binding to the E3 ubiquitin ligase cereblon, facilitating the ubiquitination of PARK7, which in turn targets PARK7 for degradation via the proteasome. JYQ-194 holds potential for research in both cancer and neurodegenerative diseases.