Glucosidase

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Glucosidases are glycoside hydrolase enzymes. α-glucosidase is a glucosidase located in the brush border of the small intestine that acts upon α(1→4) bonds. α-Glucosidase inhibitor is a new type of antidiabetics. By reducing the postprandial blood sugar concentration, it can effectively control the blood sugar levels, thereby reducing the occurrence of diabetic complications.

β-glucosidase catalyzes the hydrolysis of the glycosidic bonds to terminal non-reducing residues in β-D-glucosides and oligosaccharides, with release of glucose. β-Glucosidase has attracted substantial attention in the scientific community because of its pivotal role in cellulose degradation, glycoside transformation and many other industrial processes. β-glucosidases catalyze the final step of cellulose hydrolysis and are essential in cellulose degradation.

Glucosidase Related Products (225)
Antibodies (3)

By Effects:	Inhibitors (196) Activators (9) Modulators (3) Chemical (1) Inducer (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-161522

α-Glucosidase-IN-63	Inhibitor
α-Glucosidase-IN-63 (Compound 4d) is an inhibitor of α-Glucosidase (IC₅₀=0.44 μM). α-Glucosidase-IN-63 inhibits hCA II with an activity of K_i= 7.0 nM. α-Glucosidase-IN-63 is orally effective..

HY-151143

α-Glucosidase-IN-19	Inhibitor
α-Glucosidase-IN-19 (Compound 6B) is a potent, orally active α-glucosidase inhibitor with an IC₅₀ of 3.63 μM. α-Glucosidase-IN-19 shows anti-diabetic activity.

HY-N9051

6-Prenylquercetin-3-Me ether	Inhibitor
6-Prenylquercetin-3-Me ether is a natural product that can be extracted from G. uralensis leaves. 6-Prenylquercetin-3-Me ether has radical scavenging activity toward DPPH. 6-Prenylquercetin-3-Me ether also has inhibitory activity against α-glucosidase.

HY-150959

α-Glucosidase-IN-12	Inhibitor
α-Glucosidase-IN-12 (compound 14) is a potent α-glucosidase inhibitor, with an IC₅₀ of 10.20 μM.

HY-N7626

Eleutherol	Inhibitor
Eleutherol is a naphthalene isolated from E. americana with antifungal activities. Eleutherol is against yeasts Candida albicans, C. tropicalis, Saccharomyces cerevisiae and Cryptococcus neoformans with MIC values between 7.8 µg/mL and 250 µg/mL. Eleutherol inhibits α-glucosidase function with an IC₅₀>1.00 mM.

HY-N6575

7β-Hydroxybufalin	Inhibitor
7β-Hydroxybufalin is a bufadienolide. 7β-Hydroxybufalin can be isolated from the venom of Bufo bufo gargarizans. 7β-Hydroxybufalin inhibits α-glucosidase and acetylcholinesterase.

HY-119593

α-Homonojirimycin	Inhibitor
α-Homonojirimycin is a potent α-glucosidase inhibitor.

HY-156380

α-Amylase/α-Glucosidase-IN-6	Inhibitor
α-Amylase/α-Glucosidase-IN-6 (compound 5j) is a potent dual inhibitor of α-amylase and α-glucosidase, with IC₅₀s of 17.0 and 40.1 µM, respectively. α-Amylase/α-Glucosidase-IN-6 exhibits anti-hyperglycemic activities.

HY-N10426

(+)-Cembrene A	Inhibitor
(+)-Cembrene A (Compound 5) is a α-glucosidase inhibitor with an IC₅₀ of 30.31 μM. (+)-Cembrene A is nontoxic towards human normal hepatocyte (LO2) cells.

HY-N3101

Pedalitin	Inhibitor
Pedalitin is a inhibitor of tyrosinase（IC₅₀=0.28 mM） and α-glucosidase（IC₅₀=0.29 mM）.

HY-126067

(-)-Pinoresinol	Inhibitor
(-)-Pinoresinol is a plant-derived tetrahydrofuran lignan that inhibits α-glucosidase and acts as a hypoglycemic agent. (-)-Pinoresinol has some anti-inflammatory effects and acts as a chemopreventive agent, inducing increased apoptosis and cell cycle G2/M arrest.

HY-151138

α-Glucosidase-IN-16	Inhibitor
α-Glucosidase-IN-16 is a potent and orally active α-glucosidase inhibitor with an IC₅₀ value of 3.28 μM. α-Glucosidase-IN-16 can reduce the level of blood glucose in Streptozotocin-induced diabetic rats. Antidiabetic activity.

HY-N12664

α-Glucosidase-IN-54	Inhibitor
α-Glucosidase-IN-54 (compound 2) is a α-glucosidase inhibitor with the IC₅₀ of 0.011 mM, and can be isolated form Syzygium jambos (L.). α-Glucosidase-IN-54 can be used for study of diabetes.

HY-163332

MPO-IN-6	Inhibitor
MPO-IN-6 (compound ADC) is an electrophile with good antioxidant and anti-inflammatory properties. MPO-IN-6 is a myeloperoxidase (MPO), dipeptidyl peptidase-4 (DPP-4), and α-glucosidase (α-GD) inhibitor with IC₅₀s of 10 μM, 31.02 μM, and 46.05 μM, respectively. MPO-IN-6 is a potential cardiovascular preventive agent.

HY-149342

α-Glucosidase-IN-29	Inhibitor
α-Glucosidase-IN-29 (compound 19) is a α-glucosidases inhibitor (IC₅₀=1.21 μM, Ki=1.80 μM). α-Glucosidase-IN-29 ca be used for research of diabetes and related diseases.

HY-145275

EB-0176	Inhibitor
EB-0176 is a potent inhibitor of ER α-glucosidases (α-Glu) Iand II with IC₅₀s of 0.6439 and 0.0011 μM, respectively. EB-0176 is a N-substituted derivative of valiolamine with broad-spectrum antiviral. EB-0176 has the potential for the reseach of broad-spectrum agent against the existing and emerging viruses.

HY-114615

AMP-Deoxynojirimycin	Inhibitor
AMP-Deoxynojirimycin (AMP-DNM) is a potent ceramide glucosyltransferase and GCase 2 inhibitor. AMP-Deoxynojirimycin also is a GlcCer biosynthesis inhibitor.

HY-150723

PBI-6DNJ	Inhibitor
PBI-6DNJ is an orally active and potent multivalent glycosidase inhibitor. PBI-6DNJ exhibits good inhibition activity against α-glucosidase from mice, with a K_i of 0.14 μM. PBI-6DNJ exhibits good hypoglycemic activity. PBI-6DNJ can be used for type 2 diabetes research.

HY-163433

α-Glucosidase-IN-57	Inhibitor
α-Glucosidase-IN-57 (Compound 10c) is a competitive and orally active α-glucosidase inhibitor with an IC₅₀ value of 0.180 μM and a K_i of 0.15 μM. α-Glucosidase-IN-57 can reduce fasting and overall blood glucose levels in mice, and can be used for anti-diabetes research.

HY-162451

Antibacterial agent 207	Inducer
Antibacterial agent 207 (Compound Ru1) has antibacterial activity against S. aureus (MIC: 1 μg/mL), and low resistance frequencies. Antibacterial agent 207 destroys the bacterial cell membrane, promote production of ROS in bacteria.

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Glucosidase

Glucosidase

Glucosidase Related Products (225)

Antibodies (3)

Glucosidase Related Products (225):