2-Deoxy-2-sulfoamino-D-glucose sodium (Synonyms: D-Glucosamine-2-N-sulfate sodium)

Cat. No.: HY-107785: FAQs
Data Sheet Handling Instructions

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2-Deoxy-2-sulfoamino-D-glucose sodium (D-Glucosamine-2-N-sulfate sodium) is an endogenous metabolite. The main regulatory mechanism of 2-Deoxy-2-sulfoamino-D-glucose sodium involves the interaction of sulfuric acid groups with biomolecules. Sulfate groups can influence the charge density and configuration of polysaccharides, thereby regulating their ability to bind to proteins such as antithrombin. This combination can enhance the activity of antithrombin, which in turn inhibits key enzymes in the blood clotting process to achieve anti-clotting effects. 2-Deoxy-2-sulfoamino-D-glucose sodium can be used to study the selective removal of n-sulfate groups from Heparin (HY-17567) which has important implications for understanding the biological activity of heparin and developing related drugs.

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2-Deoxy-2-sulfoamino-D-glucose sodium Chemical Structure

CAS No. : 38899-05-7

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Description

Molecular Weight

281.22

Formula

C₆H₁₂NNaO₈S

CAS No.

38899-05-7

SMILES

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](C=O)NS(=O)(O[Na])=O

Structure Classification

Saccharides

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

H₂O : 125 mg/mL (444.49 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.5559 mL	17.7797 mL	35.5593 mL
5 mM	0.7112 mL	3.5559 mL	7.1119 mL
10 mM	0.3556 mL	1.7780 mL	3.5559 mL

View the Complete Stock Solution Preparation Table

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Nagasawa K, et al. Solvolytic desulfation of 2-deoxy-2-sulfoamino-D-glucose and D-glucose 6-sulfate[J]. Carbohydrate Research, 1974, 36(2): 265-271. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	3.5559 mL	17.7797 mL	35.5593 mL	88.8984 mL
	5 mM	0.7112 mL	3.5559 mL	7.1119 mL	17.7797 mL
	10 mM	0.3556 mL	1.7780 mL	3.5559 mL	8.8898 mL
	15 mM	0.2371 mL	1.1853 mL	2.3706 mL	5.9266 mL
	20 mM	0.1778 mL	0.8890 mL	1.7780 mL	4.4449 mL
	25 mM	0.1422 mL	0.7112 mL	1.4224 mL	3.5559 mL
	30 mM	0.1185 mL	0.5927 mL	1.1853 mL	2.9633 mL
	40 mM	0.0889 mL	0.4445 mL	0.8890 mL	2.2225 mL
	50 mM	0.0711 mL	0.3556 mL	0.7112 mL	1.7780 mL
	60 mM	0.0593 mL	0.2963 mL	0.5927 mL	1.4816 mL
	80 mM	0.0444 mL	0.2222 mL	0.4445 mL	1.1112 mL
	100 mM	0.0356 mL	0.1778 mL	0.3556 mL	0.8890 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

2-Deoxy-2-sulfoamino-D-glucose sodium Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Deoxy-2-sulfoamino-D-glucose38899-05-7D-Glucosamine-2-N-sulfateEndogenous MetaboliteSulfate groupHeparinMetabolitePolysaccharide configurationCharge densityInhibitorinhibitorinhibit

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